Coil up on the couch and prepare yourself for more action, more danger and more snakes! The giant anacondas are back in the next chapter in the thrilling series, starring David Hasselhoff as Hammett, the ruthless mercenary and snake slayer. In a secret research facility, two mega snakes are undergoing testing by a brilliant scientist, Amanda (Crystal Allen).
But when the financier, Murdoch (John Rhys-Davies), pushes the experiments too far, the snakes escape, hungry and heading for civilization. What Hammett doesn’t know is that one of the snakes is expecting a litter of slithering offspring. Now the race is on to head off the snakes’ unstoppable onslaught before they reach the city.